Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.46 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30393198 | 0.96 | EGFR (0.50) | EGFRERBB2MAPK7PDE10AKIT | |
| SCHEMBL26099028 | 0.96 | EGFR (0.50) | EGFRERBB2MAPK7PDE10AKIT | |
| SCHEMBL26103317 | 0.94 | EGFR (0.48) | EGFRERBB2MAPK7PDE10AKIT | |
| SCHEMBL26103463 | 0.90 | MAPK7 (0.44) | EGFRERBB2MAPK7PDE10AKIT | |
| SCHEMBL26101018 | 0.88 | EGFR (0.47) | EGFRERBB2MAPK7PDE10AKIT | |
| SCHEMBL26099862 | 0.88 | MAPK7 (0.45) | EGFRERBB2MAPK7PDE10AKIT | |
| SCHEMBL30891778 | 0.88 | MAPK7 (0.45) | EGFRERBB2MAPK7PDE10AKIT | |
| SCHEMBL26101421 | 0.87 | MAPK7 (0.43) | EGFRMAPK7PDE10AKIT | |
| SCHEMBL26101193 | 0.87 | MAPK7 (0.43) | EGFRMAPK7PDE10AKIT | |
| SCHEMBL26100970 | 0.86 | EGFR (0.45) | EGFRERBB2MAPK7KITBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |