Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19897758 | 1.00 | MAOB (0.67) | MAOBALDH1A1HTTPOLBDRD2 | |
| SCHEMBL23327746 | 0.91 | MAOB (0.69) | MAOBALDH1A1HTTPOLBMAOA | |
| SCHEMBL29795224 | 0.91 | MAOB (0.69) | MAOBALDH1A1HTTPOLBMAOA | |
| Bromide SCHEMBL28842080 | 0.90 | MAOB (0.67) | MAOBALDH1A1HTTPOLBMAOA | |
| SCHEMBL10801659 | 0.83 | MAOB (0.67) | MAOBALDH1A1HTTPOLBMAPT | |
| SCHEMBL7162438 | 0.83 | MAOB (0.62) | MAOBALDH1A1HTTMAPTKMT2A | |
| SCHEMBL24628659 | 0.82 | MAOB (0.74) | MAOBMRGPRX4 | |
| SCHEMBL2801030 | 0.81 | MAOB (0.60) | MAOBALDH1A1HTTMAPTKMT2A | |
| SCHEMBL13883739 | 0.81 | MAOB (0.64) | MAOBALDH1A1HTTMAPTKMT2A | |
| SCHEMBL839323 | 0.81 | DRD2 (0.71) | MAOBDRD2DRD4DRD3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863146-B | Biaryl compounds as immunomodulators | 百时美施贵宝公司 | 2023-02-28 | — | — | CN | disclosed |