Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 17/20 | 0.54 |
| ▸ | PDCD1 | Q15116 | 14/20 | 0.54 |
| ▸ | VSIR | Q9H7M9 | 12/20 | 0.54 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19897696 | 1.00 | CD274 (0.54) | CD274PDCD1VSIRSCN8ANMT2 | |
| SCHEMBL19897693 | 1.00 | CD274 (0.54) | CD274PDCD1VSIRSCN8ANMT2 | |
| SCHEMBL19897542 | 0.92 | CD274 (0.50) | CD274PDCD1VSIRALDH1A1 | |
| SCHEMBL19897541 | 0.92 | CD274 (0.50) | CD274PDCD1VSIRALDH1A1 | |
| SCHEMBL30394665 | 0.86 | CD274 (0.59) | CD274PDCD1VSIR | |
| SCHEMBL19897882 | 0.86 | CD274 (0.59) | CD274PDCD1VSIR | |
| SCHEMBL19897881 | 0.86 | CD274 (0.59) | CD274PDCD1VSIR | |
| SCHEMBL19937803 | 0.86 | SCN8A (0.53) | CD274PDCD1VSIRSCN8ANMT2 | |
| SCHEMBL19897912 | 0.84 | PDCD1 (0.60) | CD274PDCD1VSIRSCN8ANMT2 | |
| SCHEMBL30394805 | 0.84 | PDCD1 (0.60) | CD274PDCD1VSIRSCN8ANMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863146-B | Biaryl compounds as immunomodulators | 百时美施贵宝公司 | 2023-02-28 | — | — | CN | claimed |
| CN-109863146-B | Biaryl compounds as immunomodulators | 百时美施贵宝公司 | 2023-02-28 | — | — | CN | disclosed |