Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 7/20 | 0.52 |
| ▸ | KIT | P10721 | 2/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.51 |
| ▸ | FLT1 | P17948 | 5/20 | 0.51 |
| ▸ | FLT4 | P35916 | 5/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.51 |
| ▸ | TEK | Q02763 | 2/20 | 0.51 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.51 |
| ▸ | CIT | O14578 | 1/20 | 0.51 |
| ▸ | GAK | O14976 | 1/20 | 0.51 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.51 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | STK10 | O94804 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26100068 | 1.00 | EGFR (0.57) | EGFRACHEBACE1KDRKIT | |
| Hydrochloric Acid SCHEMBL30891771 | 0.87 | KDR (0.51) | EGFRACHEBACE1KDRKIT | |
| Hydrochloric Acid SCHEMBL26098361 | 0.87 | KDR (0.51) | EGFRACHEBACE1KDRKIT | |
| SCHEMBL31137830 | 0.86 | PDGFRB (0.48) | EGFRACHEBACE1KDRKIT | |
| SCHEMBL26101392 | 0.86 | PDGFRB (0.48) | EGFRACHEBACE1KDRKIT | |
| SCHEMBL30393893 | 0.86 | EGFR (0.64) | EGFRKDRKITFGFR1FLT1 | |
| Hydrochloric Acid SCHEMBL26100747 | 0.83 | KDR (0.52) | EGFRACHEBACE1KDRKIT | |
| Hydrochloric Acid SCHEMBL30891808 | 0.83 | KDR (0.52) | EGFRACHEBACE1KDRKIT | |
| SCHEMBL26100098 | 0.82 | EGFR (0.56) | EGFRKDRKITFGFR1FLT1 | |
| SCHEMBL26100102 | 0.82 | EGFR (0.62) | EGFRKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |