Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25255965 | 1.00 | DDB1 (0.46) | DDB1CRBNGPR119RORCKDM4E | |
| SCHEMBL22059965 | 0.90 | RORC (0.46) | DDB1CRBNGPR119RORCKDM4E | |
| SCHEMBL31639929 | 0.85 | DDB1 (0.47) | DDB1CRBNGPR119RORCKDM4E | |
| SCHEMBL30395072 | 0.84 | DDB1 (0.46) | DDB1CRBNGPR119RORCKDM4E | |
| SCHEMBL20757383 | 0.84 | DDB1 (0.46) | DDB1CRBNGPR119RORCKDM4E | |
| SCHEMBL29497069 | 0.84 | DDB1 (0.46) | DDB1CRBNGPR119RORCKDM4E | |
| SCHEMBL24989018 | 0.84 | DDB1 (0.46) | DDB1CRBNGPR119RORCKDM4E | |
| SCHEMBL255448 | 0.84 | ALOX5AP (0.47) | DDB1CRBNRORCKDM4EPDE4B | |
| SCHEMBL255458 | 0.84 | DDB1 (0.46) | DDB1CRBNGPR119RORCKDM4E | |
| SCHEMBL30394540 | 0.84 | DDB1 (0.46) | DDB1CRBNGPR119RORCKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-115989228-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-04-18 | — | — | CN | disclosed |