Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 11/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24190633 | 1.00 | RHEB (0.60) | RHEBGRIN1MEN1CYP2C9HPGD | |
| SCHEMBL30396548 | 0.85 | ULK1 (0.48) | RHEBGRIN1HPGDKDM4ECYP1A2 | |
| SCHEMBL24190632 | 0.85 | ULK1 (0.48) | RHEBGRIN1HPGDKDM4ECYP1A2 | |
| SCHEMBL24020641 | 0.81 | RHEB (0.64) | RHEBGRIN1MEN1CYP2C9HPGD | |
| SCHEMBL30304202 | 0.80 | RHEB (0.60) | RHEBGRIN1MEN1CYP2C9HPGD | |
| SCHEMBL28589604 | 0.78 | SRD5A2 (0.40) | RHEBGRIN1HPGDKMT2AKDM4E | |
| SCHEMBL20536067 | 0.76 | RHEB (0.81) | RHEBGRIN1MEN1CYP2C9HPGD | |
| SCHEMBL20536377 | 0.75 | RHEB (1.00) | RHEBGRIN1MEN1CYP2C9HPGD | |
| SCHEMBL29531428 | 0.75 | GRIN1 (1.00) | RHEBGRIN1MEN1CYP2C9HPGD | |
| SCHEMBL727389 | 0.75 | GRIN1 (1.00) | RHEBGRIN1MEN1CYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |