Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24190659 | 1.00 | TDP1 (0.48) | TDP1ERN1POLBHTR2CHTR2B | |
| SCHEMBL3663943 | 0.92 | TDP1 (0.44) | TDP1ERN1POLBSLC6A4HTR6 | |
| SCHEMBL14784352 | 0.81 | ERN1 (0.44) | TDP1ERN1POLBHTR2CHTR2B | |
| SCHEMBL7662729 | 0.80 | POLB (0.45) | TDP1ERN1POLBSLC6A4HTR6 | |
| SCHEMBL29333351 | 0.79 | POLB (0.47) | ERN1POLBSLC6A4HTR6 | |
| SCHEMBL29952250 | 0.79 | POLB (0.40) | POLBRORC | |
| SCHEMBL275626 | 0.79 | POLB (0.44) | TDP1ERN1POLBSLC6A4HTR6 | |
| SCHEMBL20570322 | 0.77 | KMT2A (0.46) | TDP1ERN1 | |
| SCHEMBL274642 | 0.76 | ERN1 (0.40) | TDP1ERN1HTR2CHTR2B | |
| SCHEMBL275979 | 0.76 | CHEK1 (0.42) | TDP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |