Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30396359 | 0.92 | TDP1 (0.48) | TDP1POLBSLC6A4HTR6ERN1 | |
| SCHEMBL24190659 | 0.92 | TDP1 (0.48) | TDP1POLBSLC6A4HTR6ERN1 | |
| SCHEMBL275626 | 0.88 | POLB (0.44) | TDP1POLBSLC6A4HTR6CSNK2A1 | |
| SCHEMBL7662729 | 0.86 | POLB (0.45) | TDP1POLBSLC6A4HTR6CSNK2A1 | |
| SCHEMBL14784352 | 0.84 | ERN1 (0.44) | TDP1POLBSLC6A4HTR6CSNK2A1 | |
| Formic Acid SCHEMBL28317611 | 0.78 | KMO (0.40) | SLC6A4HTR6CSNK2A1HPGDNPSR1 | |
| SCHEMBL22809712 | 0.78 | SCN8A (0.47) | POLBSLC6A4HPGD | |
| SCHEMBL7418526 | 0.77 | ALDH1A1 (0.63) | POLBERN1PDE4B | |
| SCHEMBL11779563 | 0.77 | SRC (0.49) | TDP1POLBHPGDNPSR1 | |
| SCHEMBL21643936 | 0.76 | POLB (0.45) | POLBPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2237884-A1 | CATALYST COMPLEX AND PROCESS FOR PRODUCING MULTIMODAL MOLECULAR WEIGHT POLYOLEFINS | Saudi Basic Industries Corporation (SA) | 2010-10-13 | — | — | EP | disclosed |
| WO-2008119431-A1 | CATALYST COMPLEX AND PROCESS FOR PRODUCING MULTIMODAL MOLECULAR WEIGHT POLYOLEFINS | SAUDI BASIC INDUSTRIES CORPORATION (SA) | 2008-10-09 | — | — | WO | disclosed |