Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 10/20 | 0.63 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20536129 | 0.87 | XDH (0.60) | RHEBGRIN1KMT2AEIF4A3KDM4E | |
| SCHEMBL30395343 | 0.87 | XDH (0.60) | RHEBGRIN1KMT2AEIF4A3KDM4E | |
| SCHEMBL20536179 | 0.83 | RHEB (0.63) | RHEBGRIN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL7879891 | 0.80 | RHEB (0.50) | RHEBGRIN1KMT2AEIF4A3GPR17 | |
| SCHEMBL20536067 | 0.79 | RHEB (0.81) | RHEBGRIN1KMT2AKDM4ELMNA | |
| SCHEMBL20536585 | 0.78 | RHEB (1.00) | RHEBGRIN1KMT2AEIF4A3KDM4E | |
| SCHEMBL20536254 | 0.77 | RHEB (1.00) | RHEB | |
| SCHEMBL20536026 | 0.77 | RHEB (0.77) | RHEBGRIN1KMT2ACYP2C9BLM | |
| SCHEMBL8867831 | 0.76 | KMT2A (0.55) | RHEBGRIN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL29531428 | 0.75 | GRIN1 (1.00) | RHEBGRIN1KMT2AEIF4A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |