Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.54 |
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RHEB | Q15382 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 2/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24189649 | 1.00 | BRD4 (0.54) | BRD4XDHGLAGAAKDM4E | |
| SCHEMBL30396542 | 0.87 | HPGD (0.51) | BRD4KDM4EHSD17B10RHEBHPGD | |
| SCHEMBL24189547 | 0.87 | HPGD (0.51) | BRD4KDM4EHSD17B10RHEBHPGD | |
| SCHEMBL8324363 | 0.84 | GAA (0.60) | BRD4XDHGLAGAAKDM4E | |
| SCHEMBL30396083 | 0.82 | RHEB (0.47) | GLAGAAKDM4EHSD17B10RHEB | |
| SCHEMBL8319918 | 0.81 | GLA (0.48) | BRD4XDHGLAGAAKDM4E | |
| SCHEMBL7881844 | 0.81 | RHEB (0.44) | BRD4GAAKDM4ERHEBHPGD | |
| SCHEMBL8323011 | 0.80 | GAA (0.44) | BRD4XDHGLAGAAKDM4E | |
| SCHEMBL7881841 | 0.79 | RHEB (0.45) | BRD4KDM4ERHEBHPGDESRRA | |
| SCHEMBL1277561 | 0.78 | XDH (0.59) | BRD4XDHGLAGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |