SCHEMBL30396809

SCHEMBL30396809

c1ccc2c(c1)CCC1CNCCN21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 19/20 1.00
HTR2B P41595 18/20 1.00
HTR2A P28223 5/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3265754 1.00 HTR2C (1.00) HTR2CHTR2BHTR2A
Hydrochloric Acid SCHEMBL7233743 0.98 HTR2C (0.97) HTR2CHTR2BHTR2A
SCHEMBL24187385 0.91 HTR2C (0.83) HTR2CHTR2BHTR2A
SCHEMBL691824 0.91 HTR2C (0.83) HTR2CHTR2BHTR2A
SCHEMBL15202984 0.87 HTR2C (0.77) HTR2CHTR2BHTR2A
SCHEMBL21788625 0.84 HTR2C (0.73) HTR2CHTR2BHTR2A
SCHEMBL5322262 0.83 HTR2C (0.73) HTR2CHTR2BHTR2A
SCHEMBL1366067 0.83 HTR2C (0.73) HTR2CHTR2BHTR2A
SCHEMBL692120 0.82 HTR2C (0.69) HTR2CHTR2BHTR2A
SCHEMBL19878681 0.79 HTR2C (1.00) HTR2CHTR2BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115720578-A Tricyclic derivative, preparation method and medical application thereof 深圳信立泰药业股份有限公司 2023-02-28 CN disclosed