Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13240716 | 0.90 | BTK (0.63) | BTKHPGDCA1CA2EPHX1 | |
| SCHEMBL19054658 | 0.90 | BTK (0.63) | BTKHPGDCA1CA2EPHX1 | |
| SCHEMBL20416155 | 0.90 | BTK (0.63) | BTKHPGDCA1CA2EPHX1 | |
| SCHEMBL23708984 | 0.89 | HPGD (0.56) | BTKHPGDCA1CA2EPHX1 | |
| SCHEMBL23684119 | 0.89 | HPGD (0.56) | BTKHPGDCA1CA2EPHX1 | |
| SCHEMBL30397928 | 0.88 | BTK (0.61) | BTKHPGDCA1CA2EPHX1 | |
| SCHEMBL29983871 | 0.85 | BTK (0.58) | BTKHPGDCA1CA2EPHX1 | |
| SCHEMBL1159629 | 0.84 | CA1 (0.67) | BTKHPGDCA1CA2EPHX1 | |
| SCHEMBL1159627 | 0.84 | CA1 (0.67) | BTKHPGDCA1CA2EPHX1 | |
| SCHEMBL19215254 | 0.83 | BTK (0.61) | BTKHPGDCA1CA2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |