Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30397102 | 0.88 | BTK (0.66) | BTKEPHX2CA1CA2SMN1; SMN2 | |
| SCHEMBL20416155 | 0.86 | BTK (0.63) | BTKRECQLEPHX2CA1CA2 | |
| SCHEMBL19054658 | 0.86 | BTK (0.63) | BTKRECQLEPHX2CA1CA2 | |
| SCHEMBL13240716 | 0.86 | BTK (0.63) | BTKRECQLEPHX2CA1CA2 | |
| SCHEMBL1226780 | 0.86 | RECQL (0.63) | BTKRECQLCA1CA2USP2 | |
| SCHEMBL2296901 | 0.86 | RECQL (0.63) | BTKRECQLCA1CA2USP2 | |
| SCHEMBL29983871 | 0.81 | BTK (0.58) | BTKRECQLCA1CA2SMN1; SMN2 | |
| SCHEMBL1159629 | 0.78 | CA1 (0.67) | BTKCA1CA2CTSKHPGD | |
| SCHEMBL1159627 | 0.78 | CA1 (0.67) | BTKCA1CA2CTSKHPGD | |
| SCHEMBL7205713 | 0.78 | BTK (0.78) | BTKEPHX2CA1CA2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |