⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532970 | 0.76 | — | — | |
| SCHEMBL10481926 | 0.73 | — | — | |
| SCHEMBL11995816 | 0.73 | — | — | |
| SCHEMBL8853603 | 0.70 | — | — | |
| SCHEMBL13656076 | 0.70 | — | — | |
| Methyl Phosphonate SCHEMBL9815625 | 0.67 | CA2 (0.73) | — | |
| SCHEMBL13656092 | 0.67 | — | — | |
| SCHEMBL36989 | 0.67 | — | — | |
| SCHEMBL440980 | 0.67 | — | — | |
| SCHEMBL27742289 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160297774-A1 | SUBSTITUTED QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | ARAXES PHARMA LLC | 2016-10-13 | — | — | US | disclosed |
| US-8901072-B2 | Glycopeptide and lipoglycopeptide antibiotics with improved solubility | THE MEDICINES COMPANY (US) | 2014-12-02 | — | — | US | disclosed |
| US-8552054-B2 | Anticancer agents, viricides, psychological disorders | LUITPOLD PHARMACEUTICALS, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| US-20120149632-A1 | GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS WITH IMPROVED SOLUBILITY | THE MEDICINES COMPANY (US) | 2012-06-14 | — | — | US | disclosed |
| US-8173159-B2 | Solid permeable shell of a polymer resin having surface modifying compounds that can react with isocyanates | SYNGENTA LIMITED (GB) | 2012-05-08 | — | — | US | disclosed |
| US-7812180-B2 | Electropolymerisable monomers that are soluble in aqueous solution and electroactive probes that can be obtained with such monomers | BIOMERIEUX (FR) | 2010-10-12 | — | — | US | disclosed |
| US-20100216791-A1 | PYRIDINYLQUINAZOLINAMINE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS | ASTRAZENECA (SE) | 2010-08-26 | — | — | US | disclosed |
| US-20090053826-A1 | Electropolymerisable monomers that are soluble in aqueous solution and electroactive probes that can be obtained with such monomers | BIOMERIEUX (FR) | 2009-02-26 | — | — | US | disclosed |
| US-20070191333-A1 | Antibacterial agents | WARNER LAMBERT COMPANY LLC | 2007-08-16 | — | — | US | disclosed |
| US-7217815-B2 | 2-beta -modified-6-substituted adenosine analogs and their use as antiviral agents | VALEANT PHARMACEUTICALS NORTH AMERICA (US) | 2007-05-15 | — | — | US | disclosed |