Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 4/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 4/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25526368 | 1.00 | PDE10A (0.40) | PDE10APIM1HCRTR1DPP4CCR6 | |
| SCHEMBL25526404 | 0.86 | DPP4 (0.38) | PDE10APIM1HCRTR1DPP4CCR6 | |
| SCHEMBL30397353 | 0.86 | CCR6 (0.44) | PDE10APIM1HCRTR1DPP4CCR6 | |
| SCHEMBL30397242 | 0.86 | DPP4 (0.38) | PDE10APIM1HCRTR1DPP4CCR6 | |
| SCHEMBL25526391 | 0.83 | PDE10A (0.37) | PDE10APIM1HCRTR1DPP4CCR6 | |
| SCHEMBL25522973 | 0.76 | CCNK (0.40) | — | |
| SCHEMBL30397422 | 0.75 | CCNK (0.34) | HCRTR1MAPK13 | |
| SCHEMBL17220293 | 0.75 | AURKA (0.58) | PDE10APIM1HCRTR1DPP4CCR6 | |
| SCHEMBL13579863 | 0.75 | AURKA (0.58) | PDE10APIM1HCRTR1DPP4CCR6 | |
| SCHEMBL15739705 | 0.73 | HCRTR1 (0.55) | HCRTR1DPP4CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |