Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 9/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 4/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25526404 | 0.91 | DPP4 (0.38) | CCR6DPP4PIM1PDE10AHCRTR1 | |
| SCHEMBL30397242 | 0.91 | DPP4 (0.38) | CCR6DPP4PIM1PDE10AHCRTR1 | |
| SCHEMBL25526391 | 0.88 | PDE10A (0.37) | CCR6DPP4PIM1PDE10AHCRTR1 | |
| SCHEMBL30397336 | 0.86 | PDE10A (0.40) | CCR6DPP4PIM1PDE10AHCRTR1 | |
| SCHEMBL25526368 | 0.86 | PDE10A (0.40) | CCR6DPP4PIM1PDE10AHCRTR1 | |
| SCHEMBL25417681 | 0.78 | CCNK (0.48) | CCR6PIM1 | |
| SCHEMBL30396777 | 0.76 | CCNK (0.39) | — | |
| SCHEMBL25533792 | 0.75 | IGF1R (0.36) | CCR6HCRTR1 | |
| SCHEMBL30397120 | 0.75 | CDK7 (0.36) | — | |
| SCHEMBL30397946 | 0.75 | CDK7 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |