Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25524768 | 0.92 | MAPK13 (0.44) | MAPK13KMT2AL3MBTL1BTKPADI4 | |
| SCHEMBL25523600 | 0.87 | KMT2A (0.41) | MAPK13KMT2AL3MBTL1BTKALOX15 | |
| SCHEMBL25541230 | 0.87 | BTK (0.43) | MAPK13KMT2AL3MBTL1BTKPADI4 | |
| SCHEMBL25524384 | 0.86 | KMT2A (0.42) | MAPK13KMT2AL3MBTL1BTKMEN1 | |
| SCHEMBL25533067 | 0.85 | BTK (0.44) | MAPK13KMT2AL3MBTL1BTK | |
| SCHEMBL25522632 | 0.84 | MAPK13 (0.42) | MAPK13KMT2AL3MBTL1BTKMEN1 | |
| SCHEMBL25523832 | 0.84 | MAPK13 (0.43) | MAPK13KMT2AL3MBTL1BTK | |
| SCHEMBL25529347 | 0.84 | MAPK13 (0.43) | MAPK13KMT2AL3MBTL1BTK | |
| SCHEMBL25417460 | 0.83 | MAPK13 (0.42) | MAPK13KMT2AL3MBTL1BTKPADI4 | |
| SCHEMBL25516916 | 0.83 | MAPK13 (0.42) | MAPK13KMT2AL3MBTL1BTKPADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |