Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.73 |
| ▸ | RXRA | P19793 | 1/20 | 0.66 |
| ▸ | RXRB | P28702 | 1/20 | 0.66 |
| ▸ | RXRG | P48443 | 1/20 | 0.66 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | DHFR | P00374 | 1/20 | 0.56 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626627 | 1.00 | MAOB (0.73) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL9628508 | 0.87 | MAOB (0.71) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL12030885 | 0.87 | NR4A2 (0.64) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL3624161 | 0.86 | MAOB (0.73) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL1680762 | 0.85 | MAOB (1.00) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL9626584 | 0.84 | LTA4H (0.68) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL23004585 | 0.83 | MAOB (0.73) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL8414617 | 0.83 | MAOB (0.73) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL30397454 | 0.83 | MAOB (0.73) | MAOBRXRARXRBRXRGMAOA | |
| SCHEMBL4417319 | 0.83 | MAOB (0.73) | MAOBRXRARXRBRXRGMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110240557-B | Pyrrolidine amide derivatives and use thereof | 广东东阳光药业有限公司 | 2023-05-09 | — | — | CN | disclosed |