Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22575455 | 0.95 | PAOX (0.35) | PAOXADH1BADH1AADH7FDFT1 | |
| SCHEMBL12911823 | 0.83 | TSHR (0.46) | PAOXADH1BADH1AADH7KDM1A | |
| Bromide SCHEMBL28414953 | 0.82 | ALDH1A1 (0.48) | ADH1BADH1AADH7KDM1A | |
| Bromide SCHEMBL28882145 | 0.82 | ALDH1A1 (0.48) | ADH1BADH1AADH7KDM1A | |
| Bromide SCHEMBL28486310 | 0.82 | ALDH1A1 (0.48) | ADH1BADH1AADH7KDM1A | |
| Bromide SCHEMBL28529643 | 0.82 | ALDH1A1 (0.48) | ADH1BADH1AADH7KDM1A | |
| Hydrochloric Acid SCHEMBL22575422 | 0.81 | TSHR (0.44) | PAOXADH1BADH1AADH7KDM1A | |
| SCHEMBL12912298 | 0.81 | TSHR (0.52) | PAOXADH1BADH1AADH7KDM1A | |
| SCHEMBL28336030 | 0.79 | ALDH1A1 (0.50) | ADH1BADH1AADH7KDM1A | |
| Hydrochloric Acid SCHEMBL22575300 | 0.79 | TSHR (0.50) | ADH1BADH1AADH7KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075573-A | Sulfonated polymers | 沙特阿拉伯石油公司 | 2023-05-05 | — | — | CN | disclosed |