Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | KCNK3 | O14649 | 15/20 | 0.61 |
| ▸ | KCNK9 | Q9NPC2 | 15/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18963146 | 0.91 | KDM4E (0.78) | KDM4ESLC2A1GAAKCNK3KCNK9 | |
| Hydrochloric Acid SCHEMBL18952318 | 0.90 | KDM4E (0.77) | KDM4ESLC2A1GAAKCNK3KCNK9 | |
| SCHEMBL29432721 | 0.89 | KCNK3 (0.60) | KDM4ESLC2A1GAAKCNK3KCNK9 | |
| SCHEMBL17718804 | 0.84 | SLC2A1 (1.00) | KDM4ESLC2A1GAAHTT | |
| SCHEMBL18963197 | 0.82 | KDM4E (0.75) | KDM4ESLC2A1GAAKCNK3KCNK9 | |
| SCHEMBL18963131 | 0.81 | KCNK3 (0.64) | KDM4ESLC2A1GAAKCNK3KCNK9 | |
| SCHEMBL18938378 | 0.81 | SLC2A1 (0.66) | KDM4ESLC2A1GAAKCNK3KCNK9 | |
| Hydrochloric Acid SCHEMBL22260956 | 0.80 | KCNK3 (0.63) | KDM4ESLC2A1GAAKCNK3KCNK9 | |
| SCHEMBL22364213 | 0.80 | KCNK3 (0.76) | KDM4ESLC2A1GAAKCNK3KCNK9 | |
| SCHEMBL18963312 | 0.79 | KCNK3 (0.62) | KDM4ESLC2A1GAAKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4175954-A1 | COMBINATION OF AN ALPHA2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONIST WITH A TASK1/3 CHANNEL BLOCKER FOR THE TREATMENT OF SLEEP APNEA | Bayer Aktiengesellschaft (DE) | 2023-05-10 | — | — | EP | disclosed |