SCHEMBL30398484

SCHEMBL30398484

O=C(O)c1ccccc1Nc1cccc(Cl)c1-c1ccc2c(c1)CCO2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 20/20 1.00
FABP3 P05413 12/20 1.00
FABP5 Q01469 8/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28563503 1.00 FABP4 (1.00) FABP4FABP3FABP5
SCHEMBL28557161 0.89 FABP4 (0.80) FABP4FABP3FABP5
SCHEMBL30462492 0.89 FABP4 (0.80) FABP4FABP3FABP5
SCHEMBL28566382 0.87 FABP4 (1.00) FABP4FABP3FABP5
SCHEMBL28550199 0.84 FABP4 (1.00) FABP4FABP3FABP5
SCHEMBL28560288 0.81 FABP4 (0.72) FABP4FABP3FABP5
SCHEMBL28565383 0.77 FABP4 (1.00) FABP4FABP3FABP5
SCHEMBL28571367 0.77 FABP4 (1.00) FABP4FABP3FABP5
SCHEMBL30462505 0.77 FABP4 (0.82) FABP4FABP3FABP5
SCHEMBL30462449 0.76 FABP4 (0.86) FABP4FABP3FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4175647-A1 ANTIVIRAL USE OF FABP4 MODULATING COMPOUNDS Crescenta Biosciences (US) 2023-05-10 EP claimed
CN-112745237-B 2-arylamine compound and preparation method and application thereof 中国科学院上海药物研究所 2023-06-20 CN disclosed