Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 5/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 4/20 | 0.38 |
| ▸ | IL2 | P60568 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.37 |
| ▸ | CLK1 | P49759 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26175022 | 1.00 | MAP3K11 (0.40) | MAP3K11MAP4K1TNIKIL2DYRK1B | |
| SCHEMBL26175021 | 0.93 | MAP3K11 (0.36) | MAP3K11MAP4K1TNIKIL2DYRK1B | |
| SCHEMBL30400516 | 0.93 | MAP3K11 (0.36) | MAP3K11MAP4K1TNIKIL2DYRK1B | |
| SCHEMBL26174983 | 0.87 | MAP3K11 (0.53) | MAP3K11MAP4K1TNIKIL2ACACB | |
| SCHEMBL30399129 | 0.87 | MAP3K11 (0.53) | MAP3K11MAP4K1TNIKIL2ACACB | |
| SCHEMBL30399632 | 0.84 | EGLN1 (0.43) | MAP3K11MAP4K1TNIKIL2DYRK1B | |
| SCHEMBL26174944 | 0.84 | EGLN1 (0.43) | MAP3K11MAP4K1TNIKIL2DYRK1B | |
| SCHEMBL30398996 | 0.82 | DYRK1B (0.39) | MAP3K11MAP4K1TNIKIL2DYRK1B | |
| SCHEMBL26176975 | 0.82 | DYRK1B (0.39) | MAP3K11MAP4K1TNIKIL2DYRK1B | |
| SCHEMBL30400509 | 0.82 | MAP3K11 (0.51) | MAP3K11MAP4K1TNIKIL2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4415817-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AS DYRK1A INHIBITORS | BioSplice Therapeutics, Inc. (US) | 2024-08-21 | — | — | EP | claimed |
| WO-2023064349-A1 | 1H-PYRROLO[2,3-B]PYRIDINES AS DYRK1A INHIBITORS | BIOSPLICE THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | claimed |