Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 11/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25151345 | 0.82 | ALDH1A1 (0.41) | CA12CA1CA2CA9CA14 | |
| SCHEMBL25151259 | 0.79 | ALDH1A1 (0.39) | CA12CA1CA2CA9CA14 | |
| SCHEMBL25151436 | 0.78 | HSD17B10 (0.38) | CA12CA1CA2CA9CA14 | |
| SCHEMBL30398943 | 0.77 | CA12 (0.36) | CA12CA1CA2CA9CA14 | |
| SCHEMBL31211289 | 0.71 | CYP3A4 (0.39) | CA12CA1CA2CA9CA14 | |
| SCHEMBL9111534 | 0.71 | CA12 (0.49) | CA12CA1CA2CA9CA14 | |
| SCHEMBL31456683 | 0.69 | CA12 (0.47) | CA12CA1CA2CA9CA14 | |
| SCHEMBL27250755 | 0.69 | CA12 (0.40) | CA12CA1CA2CA9CA14 | |
| SCHEMBL15004634 | 0.69 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10CYP2C9CYP1A2 | |
| SCHEMBL30527437 | 0.68 | CA12 (0.60) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4416141-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | Remix Therapeutics Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064880-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-04-20 | — | — | WO | disclosed |