Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 7/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 5/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30186760 | 0.73 | TLR8 (0.43) | AADAT | |
| SCHEMBL30186684 | 0.71 | TOP2A (0.35) | AADATMAPK14 | |
| SCHEMBL30334761 | 0.70 | GRM1 (0.38) | GRM1KDM4EALDH1A1GSK3BDYRK1A | |
| SCHEMBL30327248 | 0.69 | CLK1 (0.39) | GRM1HRH3GRM5MIFGABRA1 | |
| SCHEMBL30169432 | 0.67 | ACVR1 (0.51) | HRH3KDM4EALDH1A1KMT2ANPC1 | |
| SCHEMBL8236952 | 0.65 | GRM1 (0.86) | GRM1GRM5KDM4EALDH1A1 | |
| SCHEMBL30169508 | 0.65 | GAA (0.51) | HRH3KDM4EALDH1A1KMT2ATSHR | |
| SCHEMBL30400928 | 0.64 | MIF (0.47) | MIFGABRA1KDM4EALDH1A1IDO1 | |
| SCHEMBL13801127 | 0.64 | KDM4E (0.63) | MIFGABRA1KDM4EALDH1A1IDO1 | |
| SCHEMBL15939645 | 0.64 | GRM1 (0.55) | GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096725-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2023-05-09 | — | — | CN | disclosed |