SCHEMBL30401307 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	EGLN1	Q9GZT9	13/20	0.46

▸	KDM4E	B2RXH2	1/20	0.35

▸	ALDH1A1	P00352	1/20	0.35

▸	HSD17B10	Q99714	1/20	0.35

▸	GABRA1	P14867	1/20	0.33

▸	GABRR1	P24046	1/20	0.33

▸	GABRA3	P34903	1/20	0.33

▸	GABRA2	P47869	1/20	0.33

▸	GABRB2	P47870	1/20	0.33

▸	MAOB	P27338	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18789248	1.00	EGLN1 (0.46)	EGLN1KDM4EALDH1A1HSD17B10GABRA1
SCHEMBL23929886	0.81	EGLN1 (0.39)	EGLN1GABRA1GABRR1GABRA3GABRA2
SCHEMBL30744318	0.78	EGLN1 (0.46)	EGLN1MAOB
SCHEMBL21491536	0.78	EGLN1 (0.46)	EGLN1MAOB
SCHEMBL27834602	0.78	MAP4K4 (0.43)	KDM4EALDH1A1HSD17B10GABRA1GABRR1
SCHEMBL28895212	0.78	EGLN1 (0.56)	EGLN1KDM4EALDH1A1HSD17B10
SCHEMBL17966650	0.77	EGLN1 (0.49)	EGLN1KDM4EALDH1A1
SCHEMBL17966620	0.77	EGLN1 (0.39)	EGLN1GABRA1GABRR1GABRA3GABRA2
SCHEMBL17966628	0.76	RET (0.39)	EGLN1
SCHEMBL18789296	0.76	EGLN1 (0.51)	EGLN1KDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-111423416-B	Inhibitors of RET	缆图药品公司	2023-05-26	—	—	CN	disclosed