Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 15/20 | 0.56 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930012 | 0.85 | EGLN1 (0.49) | EGLN1ALKBH1 | |
| SCHEMBL14075584 | 0.78 | LMNA (0.53) | EGLN1KDM4EALDH1A1KLKB1 | |
| SCHEMBL18789248 | 0.78 | EGLN1 (0.46) | EGLN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL30401307 | 0.78 | EGLN1 (0.46) | EGLN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL18789296 | 0.75 | EGLN1 (0.51) | EGLN1KDM4EALDH1A1HSD17B10KLKB1 | |
| SCHEMBL10691581 | 0.74 | ALDH1A1 (0.51) | KDM4EALDH1A1 | |
| SCHEMBL12989502 | 0.73 | EGLN1 (0.47) | EGLN1 | |
| SCHEMBL28938095 | 0.72 | EGLN1 (0.46) | EGLN1 | |
| SCHEMBL28938094 | 0.72 | EGLN1 (0.46) | EGLN1 | |
| SCHEMBL18806641 | 0.72 | EGLN1 (0.45) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423416-B | Inhibitors of RET | 缆图药品公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-111423416-A | Inhibitors of RET | 蓝图药品公司 | 2020-07-17 | — | — | CN | disclosed |
| CN-108473468-B | Inhibitors of RET | 蓝图药品公司 | 2020-06-16 | — | — | CN | disclosed |