Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20416870 | 1.00 | PTGDR (0.38) | PTGDRALOX12ADORA2AADORA2BADORA1 | |
| SCHEMBL20436654 | 0.93 | ADORA2A (0.39) | PTGDRALOX12ADORA2AADORA2BADORA1 | |
| SCHEMBL30401191 | 0.90 | ADORA2A (0.39) | PTGDRALOX12ADORA2AADORA2BADORA1 | |
| SCHEMBL20401313 | 0.90 | ADORA2A (0.39) | PTGDRALOX12ADORA2AADORA2BADORA1 | |
| SCHEMBL20436661 | 0.90 | KDM4E (0.41) | PTGDRALOX12ADORA2AADORA2BADORA1 | |
| SCHEMBL20436645 | 0.90 | ADORA2A (0.44) | PTGDRALOX12ADORA2AADORA2BADORA1 | |
| SCHEMBL20416742 | 0.89 | CDC7 (0.43) | PTGDRADORA2AADORA2BADORA1CYP19A1 | |
| SCHEMBL20416680 | 0.88 | CNR1 (0.36) | PTGDRALOX12ADORA2AADORA2BADORA1 | |
| SCHEMBL20416755 | 0.88 | KDM4E (0.37) | PTGDRALOX12ADORA2AADORA2BADORA1 | |
| SCHEMBL30401296 | 0.88 | KDM4E (0.37) | PTGDRALOX12ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110214012-B | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-05-09 | — | — | CN | disclosed |