Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24399588 | 1.00 | AR (0.44) | AREGFRLTA4HIDO1SCN8A | |
| SCHEMBL24399749 | 0.84 | IDO1 (0.40) | IDO1CYP3A4MAPK1 | |
| SCHEMBL30402437 | 0.84 | IDO1 (0.40) | IDO1CYP3A4MAPK1 | |
| SCHEMBL25375809 | 0.83 | AR (0.41) | ARTP53ALDH1A1 | |
| SCHEMBL30401750 | 0.81 | AR (0.41) | ARKDM4EALDH1A1GAACYP1A2 | |
| SCHEMBL24399674 | 0.81 | AR (0.41) | ARKDM4EALDH1A1GAACYP1A2 | |
| SCHEMBL30401021 | 0.80 | AR (0.43) | ARSCN8ANR3C2TP53GALR3 | |
| SCHEMBL25373892 | 0.80 | AR (0.43) | ARSCN8ANR3C2TP53GALR3 | |
| SCHEMBL25375372 | 0.77 | MBOAT4 (0.39) | EGFRLTA4HIDO1NR3C2ALDH1A1 | |
| SCHEMBL30401708 | 0.77 | MBOAT4 (0.39) | EGFRLTA4HIDO1NR3C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |