Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | TEK | Q02763 | 3/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20416781 | 1.00 | KDR (0.46) | KDRTEKEPHB4ADORA2AADORA2B | |
| SCHEMBL20442127 | 0.90 | TEK (0.47) | KDRTEKEPHB4ADORA2AADORA2B | |
| SCHEMBL20417191 | 0.90 | ADORA2A (0.46) | KDRADORA2AADORA2BADORA1 | |
| SCHEMBL30401930 | 0.89 | ADORA2A (0.46) | KDRTEKEPHB4ADORA2AADORA2B | |
| SCHEMBL20401210 | 0.89 | ADORA2A (0.46) | KDRTEKEPHB4ADORA2AADORA2B | |
| SCHEMBL30401143 | 0.89 | ADORA2A (0.46) | KDRTEKEPHB4ADORA2AADORA2B | |
| SCHEMBL20401029 | 0.89 | ADORA2A (0.46) | KDRTEKEPHB4ADORA2AADORA2B | |
| SCHEMBL20436400 | 0.89 | ADORA2A (0.47) | KDRTEKEPHB4ADORA2AADORA2B | |
| SCHEMBL20401259 | 0.88 | ADORA2A (0.43) | KDRTEKEPHB4ADORA2AADORA2B | |
| SCHEMBL20400625 | 0.87 | ADORA2A (0.43) | KDRTEKEPHB4ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768859-A | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-110214012-B | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-05-09 | — | — | CN | disclosed |