Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813862 | 0.75 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL31167726 | 0.72 | EGFR (0.30) | EGFR | |
| SCHEMBL30402699 | 0.71 | PDPK1 (0.36) | EGFR | |
| SCHEMBL13472688 | 0.71 | — | — | |
| SCHEMBL12210434 | 0.70 | — | — | |
| SCHEMBL30808059 | 0.68 | IKBKB (0.31) | — | |
| SCHEMBL21823121 | 0.67 | AXL (0.35) | HTTEGFR | |
| SCHEMBL23458477 | 0.64 | KDM4E (0.49) | — | |
| SCHEMBL4512720 | 0.63 | HTT (0.63) | HTTLMNACYP1A2CYP2D6 | |
| SCHEMBL10994146 | 0.63 | HTT (0.49) | HTTLMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4430022-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | Vigil Neuroscience, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086801-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |