SCHEMBL23458477

SCHEMBL23458477

c1cc(-c2nc3ncncc3s2)ccn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
PIK3CD O00329 1/20 0.43
PIK3CA P42336 1/20 0.43
PIK3CB P42338 1/20 0.43
PIK3CG P48736 1/20 0.43
CDC7 O00311 4/20 0.37
DBF4 Q9UBU7 4/20 0.37
CYP19A1 P11511 3/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MAPT P10636 1/20 0.37
IDO1 P14902 3/20 0.36
TDO2 P48775 3/20 0.36
POLB P06746 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK9 P45984 1/20 0.35
MAPK10 P53779 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23458481 0.77 KDM4E (0.59) KDM4ENPC1RAB9APIK3CDPIK3CA
Hydrochloric Acid SCHEMBL23458577 0.74 KDM4E (0.33) KDM4ENPC1RAB9ACDC7DBF4
SCHEMBL23458521 0.73 NPC1 (0.68) KDM4ENPC1RAB9APIK3CDPIK3CA
SCHEMBL23486249 0.72 KDM4E (0.34) KDM4ENPC1RAB9AALDH1A1HPGD
SCHEMBL23458512 0.72 PIK3CA (0.54) KDM4ENPC1RAB9APIK3CDPIK3CA
SCHEMBL23458575 0.72
SCHEMBL29414542 0.71 KDM4E (0.50) KDM4ENPC1RAB9APIK3CDPIK3CA
SCHEMBL22322876 0.70 KDM4E (0.50) KDM4ENPC1RAB9APIK3CDPIK3CA
SCHEMBL31167726 0.70 EGFR (0.30)
SCHEMBL23458507 0.69 RAB9A (0.68) KDM4ENPC1RAB9APIK3CDPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021110890-A1 PYRIDINIUM DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-06-10 WO disclosed
WO-2021110890-A1 PYRIDINIUM DERIVATIVES AS HERBICIDES SYNGENTA CROP PROTECTION AG (CH) 2021-06-10 WO disclosed