Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20401393 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HPGDHSD17B10NPC1MAPT | |
| SCHEMBL20401331 | 0.98 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10NPC1MAPT | |
| SCHEMBL30401911 | 0.98 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10NPC1MAPT | |
| SCHEMBL20436675 | 0.93 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10NPC1MAPT | |
| SCHEMBL20436674 | 0.91 | ALDH1A1 (0.40) | ALDH1A1HPGDHSD17B10NPC1MAPT | |
| SCHEMBL30400427 | 0.85 | ADORA2A (0.41) | ADORA2AADORA2BADORA1CDK2ADORA3 | |
| SCHEMBL20400314 | 0.85 | ADORA2A (0.41) | ADORA2AADORA2BADORA1CDK2ADORA3 | |
| SCHEMBL20400402 | 0.84 | ADORA2A (0.36) | ALDH1A1HPGDMAPTADORA2AADORA2B | |
| SCHEMBL30401183 | 0.84 | ADORA2A (0.36) | ALDH1A1HPGDMAPTADORA2AADORA2B | |
| SCHEMBL20401421 | 0.84 | CDC7 (0.41) | ADORA2AADORA2BADORA1CDK2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768859-A | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-110214012-B | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-05-09 | — | — | CN | disclosed |