Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 11/20 | 0.66 |
| ▸ | BRAF | P15056 | 8/20 | 0.61 |
| ▸ | KDR | P35968 | 4/20 | 0.61 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.61 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.61 |
| ▸ | CSF1R | P07333 | 4/20 | 0.54 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.54 |
| ▸ | DDR2 | Q16832 | 4/20 | 0.54 |
| ▸ | LCK | P06239 | 3/20 | 0.52 |
| ▸ | TEK | Q02763 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16735236 | 1.00 | RAF1 (0.66) | RAF1BRAFKDRPDGFRBPDGFRA | |
| SCHEMBL15066274 | 0.83 | RAF1 (0.79) | RAF1BRAFKDRPDGFRBPDGFRA | |
| SCHEMBL3766543 | 0.81 | BRAF (0.56) | RAF1BRAFKDRPDGFRBPDGFRA | |
| SCHEMBL24399726 | 0.81 | RAF1 (0.47) | RAF1BRAFKDRPDGFRBPDGFRA | |
| SCHEMBL30400432 | 0.81 | RAF1 (0.47) | RAF1BRAFKDRPDGFRBPDGFRA | |
| SCHEMBL29638502 | 0.80 | BRAF (0.59) | RAF1BRAFKDRPDGFRBPDGFRA | |
| SCHEMBL24399708 | 0.80 | BRAF (0.59) | RAF1BRAFKDRPDGFRBPDGFRA | |
| SCHEMBL16735369 | 0.80 | RAF1 (1.00) | RAF1BRAFKDRPDGFRBPDGFRA | |
| SCHEMBL29638591 | 0.79 | BRAF (0.49) | RAF1BRAFKDRCSF1RDDR1 | |
| SCHEMBL24399601 | 0.79 | BRAF (0.49) | RAF1BRAFKDRCSF1RDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |