Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25376257 | 1.00 | ALDH1A1 (0.47) | ALDH1A1PDE3BPDE3ATSHRTDP1 | |
| SCHEMBL21603380 | 0.83 | ALDH1A1 (0.46) | ALDH1A1PDE3BPDE3ATSHRTDP1 | |
| SCHEMBL25376149 | 0.80 | ALDH1A1 (0.53) | ALDH1A1PDE3BPDE3ATSHRTDP1 | |
| SCHEMBL30162663 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1HPGDKMT2A | |
| SCHEMBL2260806 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1HPGDKMT2A | |
| SCHEMBL17263930 | 0.77 | TSHR (0.64) | ALDH1A1TSHRTDP1KMT2ASMN1; SMN2 | |
| SCHEMBL30402475 | 0.76 | RAF1 (0.48) | ALDH1A1TDP1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL25375966 | 0.76 | RAF1 (0.48) | ALDH1A1TDP1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL25378118 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1HPGDKMT2A | |
| SCHEMBL30402505 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRTDP1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096718-A | Aryl amide compound, pharmaceutical composition containing same, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |