SCHEMBL30402952

CC(C)C[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	19/20	0.57

▸	BACE2	Q9Y5Z0	4/20	0.57

▸	CTSD	P07339	2/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29757432	0.94	BACE1 (0.48)	BACE1BACE2CTSD
SCHEMBL31039959	0.89	MME (0.45)	—
SCHEMBL30728889	0.88	MME (0.50)	BACE1
SCHEMBL29531754	0.88	MME (0.50)	BACE1
SCHEMBL29556143	0.88	ERAP2 (0.59)	BACE1BACE2
SCHEMBL30974452	0.87	BACE1 (0.39)	BACE1BACE2CTSD
SCHEMBL31253154	0.86	GLP1R (0.45)	BACE1BACE2
SCHEMBL31375132	0.86	FOLH1 (0.45)	BACE1BACE2CTSD
SCHEMBL29531673	0.86	FOLH1 (0.45)	BACE1BACE2CTSD
SCHEMBL29939815	0.86	FOLH1 (0.45)	BACE1BACE2CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-114292311-B	Pancreatic lipase inhibitory peptide and application thereof	华南理工大学	2023-05-12	—	—	CN	disclosed
CN-114292311-B	Pancreatic lipase inhibitory peptide and application thereof	华南理工大学	2023-05-12	—	—	CN	disclosed