SCHEMBL30402971

SCHEMBL30402971

NC(=O)C1CCCCN1C(=O)c1cc2ccccc2[nH]1

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 9/20 0.65
F2 P00734 1/20 0.55
F10 P00742 1/20 0.55
PLG P00747 1/20 0.55
PRSS1 P07477 1/20 0.55
HRH4 Q9H3N8 5/20 0.51
HRH3 Q9Y5N1 1/20 0.51
POLB P06746 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ITGB3 P05106 1/20 0.48
ITGA2B P08514 1/20 0.48
PDE4B Q07343 1/20 0.46
RBP4 P02753 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30310614 0.96 AKR1C3 (0.60) AKR1C3F2F10PLGPRSS1
SCHEMBL24235367 0.85 AKR1C3 (0.61) AKR1C3F2F10PLGPRSS1
SCHEMBL11981489 0.79 AKR1C3 (1.00) AKR1C3HRH4HRH3POLBSMN1; SMN2
SCHEMBL15533406 0.79 AKR1C3 (0.62) AKR1C3HRH4HRH3POLBSMN1; SMN2
SCHEMBL15064997 0.79 AKR1C3 (0.62) AKR1C3HRH4HRH3POLBSMN1; SMN2
SCHEMBL13753537 0.79 AKR1C3 (0.62) AKR1C3HRH4HRH3POLBSMN1; SMN2
SCHEMBL25040224 0.78 HRH4 (0.56) F2F10PLGPRSS1HRH4
SCHEMBL30874868 0.77 DPP4 (0.47) AKR1C3F2F10PLGPRSS1
SCHEMBL1275006 0.77 AKR1C3 (0.60) AKR1C3F2F10PLGPRSS1
SCHEMBL13201971 0.77 AKR1C3 (0.63) AKR1C3F2F10PLGPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116096714-A Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections 安力高医药股份有限公司 2023-05-09 CN disclosed