Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17544423 | 1.00 | MEN1 (0.38) | MEN1KMT2ACSF1RPDE3BPDE3A | |
| SCHEMBL29000623 | 0.85 | CSF1R (0.42) | CSF1RPDE3BPDE3ASMN1; SMN2NPC1 | |
| SCHEMBL29681201 | 0.83 | HSD17B10 (0.46) | SMN1; SMN2NPC1RAB9AMAPTAPP | |
| SCHEMBL17544365 | 0.83 | HSD17B10 (0.46) | SMN1; SMN2NPC1RAB9AMAPTAPP | |
| SCHEMBL1121632 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2APDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL30401743 | 0.80 | HSD17B10 (0.44) | SMN1; SMN2NPC1RAB9AMAPTCETP | |
| SCHEMBL17544189 | 0.80 | HSD17B10 (0.44) | SMN1; SMN2NPC1RAB9AMAPTCETP | |
| SCHEMBL30401735 | 0.80 | HSD17B10 (0.58) | SMN1; SMN2NPC1RAB9AMAPTPDE10A | |
| SCHEMBL17544499 | 0.80 | HSD17B10 (0.58) | SMN1; SMN2NPC1RAB9AMAPTPDE10A | |
| SCHEMBL17544360 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2NPC1RAB9AMAPTCETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655618-A | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-107108534-B | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2023-05-09 | — | — | CN | disclosed |