Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29000641 | 1.00 | PTPN2 (0.42) | PTPN2PTPN1PTPN5ALDH1A1HPGD | |
| SCHEMBL21572848 | 0.89 | ALDH1A1 (0.43) | PTPN2PTPN1PTPN5ALDH1A1HPGD | |
| SCHEMBL29681323 | 0.89 | PTPN2 (0.42) | PTPN2PTPN1PTPN5ALDH1A1HPGD | |
| SCHEMBL17544622 | 0.89 | PTPN2 (0.42) | PTPN2PTPN1PTPN5ALDH1A1HPGD | |
| SCHEMBL23633322 | 0.82 | SMN1; SMN2 (0.58) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL17544356 | 0.82 | MAPT (0.55) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL30402272 | 0.82 | MAPT (0.55) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL29681162 | 0.82 | MAPT (0.55) | ALDH1A1HPGDRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL17544797 | 0.82 | HSD17B10 (0.53) | PTPN2PTPN1PTPN5ALDH1A1HPGD | |
| SCHEMBL17544578 | 0.82 | ALDH1A1 (0.53) | PTPN2PTPN1PTPN5ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655618-A | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-107108534-B | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2023-05-09 | — | — | CN | disclosed |