⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2537089 | 0.97 | — | — | |
| SCHEMBL30401877 | 0.90 | — | — | |
| SCHEMBL18320895 | 0.87 | — | — | |
| SCHEMBL460688 | 0.87 | — | — | |
| SCHEMBL30401686 | 0.87 | — | — | |
| SCHEMBL460689 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL38657456 | 0.83 | — | — | |
| Bromide SCHEMBL30629032 | 0.83 | — | — | |
| SCHEMBL27457678 | 0.83 | — | — | |
| SCHEMBL31675822 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781574-B1 | MACROCYCLIC SPIROETHERS AS MCL-1 INHIBITORS | ASCENTAGE PHARMA SUZHOU CO LTD (CN) | 2023-05-10 | — | — | EP | disclosed |