SCHEMBL460688

SCHEMBL460688

C1=C\C=C/N=C\C=C/1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL460689 1.00
SCHEMBL18320895 1.00
SCHEMBL30401686 1.00
Bromide SCHEMBL30629032 0.96
Hydrochloric Acid SCHEMBL38657456 0.96
SCHEMBL27457678 0.96
SCHEMBL31675822 0.89
SCHEMBL31645514 0.87
SCHEMBL30403277 0.87
SCHEMBL31676163 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 902 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076059-A1 ROCAGLATE DERIVATIVES AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2025-04-10 WO claimed
CN-119072466-A Compositions, formulations and methods for skin treatment 奇特实验室有限责任公司 2024-12-03 CN claimed
EP-4460493-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT Oddity Labs, LLC (US) 2024-11-13 EP claimed
US-12122958-B2 Loss circulation material SAUDI ARABIAN OIL COMPANY (SA) 2024-10-22 US claimed
US-20240294820-A1 Loss Circulation Material SAUDI ARABIAN OIL COMPANY (SA) 2024-09-05 US claimed
EP-4412991-A1 DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS AZORA THERAPEUTICS, INC. (US) 2024-08-14 EP claimed
CN-118317948-A Derivatives of aromatic hydrocarbon receptor agonists 阿佐拉治疗股份有限公司 2024-07-09 CN claimed
WO-2023133240-A1 COMPOSITIONS, FORMULATIONS, AND METHODS FOR SKIN TREATMENT REVELA, INC. (US) 2023-07-13 WO claimed
WO-2023060268-A1 DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS AZORA THERAPEUTICS, INC. (US) 2023-04-13 WO claimed
US-11613649-B2 Thermally-rearranged polymer blends for gas separation membranes BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-03-28 US claimed
US-20100298569-A1 USE OF CYCLOVINYL PHOSPHINE/COPPER COMPLEXES AS ARYLATION CATALYSTS CENTRE NATIONAL DE RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2010-11-25 US claimed
EP-2197889-A2 USE OF CYCLOVINYL PHOSPHINE/COPPER COMPLEXES AS ARYLATION CATALYSTS Centre National de la Recherche Scientifique (C.N.R.S.) (FR) 2010-06-23 EP claimed
WO-2009050394-A2 USE OF CYCLOVINYL PHOSPHINE/COPPER COMPLEXES AS ARYLATION CATALYSTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2009-04-23 WO claimed
US-6667304-B2 Affinity for melatonin receptors; sleep disorders; N-(2-(2-methoxy-6H-pyrido(2',3':4,5)pyrrolo(2,1-a)isoindol-11 -yl)ethyl)acetamide; N-(2-(3-methoxy-6,7,8,9-tetrahydropyrido (3,2-b)indolizin-5-yl) ethyl)acetamide LES LABORATOIRES SERVIER (FR) 2003-12-23 US claimed
US-20030134847-A1 New polycyclic azaindole compounds GUILLAUMET GERALD (FR) 2003-07-17 US claimed
US-20030105087-A1 For therapy of melatoninergic disorders GUILLAUMET GERALD (FR) 2003-06-05 US claimed
EP-1092717-B1 Polycyclic azaindole derivatives, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-01-08 EP claimed
US-6495543-B1 TREATING OR PREVENTING MELATONINERGIC DISORDERS LES LABORATOIRES SERVIER (FR) 2002-12-17 US claimed
EP-1092717-A2 Polycyclic azaindole derivatives, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 2001-04-18 EP claimed
CN-87102916-A Benzimidazole sulfonamides and imidazopyridine sulfonamides, their preparation and their use as pharmaceuticals 1988-04-27 CN claimed