SCHEMBL30403281

SCHEMBL30403281

COc1ccc2[nH]c(C(=O)O)cc2c1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.60
HPGD P15428 3/20 0.60
KMT2A Q03164 6/20 0.55
MEN1 O00255 5/20 0.55
MAPT P10636 4/20 0.55
ALDH1A1 P00352 3/20 0.55
LMNA P02545 3/20 0.55
POLB P06746 1/20 0.55
PTBP1 P26599 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
BLM P54132 1/20 0.54
HSD17B10 Q99714 1/20 0.49
IDO1 P14902 2/20 0.48
TDO2 P48775 2/20 0.48
TDP1 Q9NUW8 1/20 0.45
FLT3 P36888 2/20 0.45
SRD5A2 P31213 2/20 0.45
NGFR P08138 1/20 0.44
SRD5A1 P18405 1/20 0.44
PIN1 Q13526 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6240318 1.00 KDM4E (0.60) KDM4EHPGDKMT2AMEN1MAPT
SCHEMBL38660125 0.87 KDM4E (0.54) KDM4EHPGDKMT2AMEN1MAPT
SCHEMBL4785003 0.86 KMT2A (0.54) KDM4EHPGDKMT2AMEN1MAPT
SCHEMBL5564109 0.86 KMT2A (0.57) KDM4EHPGDKMT2AMEN1MAPT
SCHEMBL11737870 0.84 KDM4E (0.49) KDM4EHPGDKMT2AMEN1MAPT
SCHEMBL1144884 0.84 KDM4E (0.60) KDM4EHPGDKMT2AMEN1MAPT
SCHEMBL9314516 0.84 KDM4E (0.60) KDM4EHPGDKMT2AMEN1MAPT
SCHEMBL28265787 0.84 KMT2A (0.52) KDM4EHPGDKMT2AMEN1MAPT
SCHEMBL2492396 0.83 IDO1 (0.51) KDM4EHPGDKMT2AMEN1ALDH1A1
SCHEMBL3028151 0.83 KDM4E (0.59) KDM4EHPGDKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102212-A1 MACROCYCLIC MCL-1 INHIBITORS VANDERBILT UNIVERSITY (US) 2026-05-15 WO disclosed
CN-116096714-A Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections 安力高医药股份有限公司 2023-05-09 CN disclosed