Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | NGFR | P08138 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16030401 | 0.86 | CYP1A2 (0.45) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL16031847 | 0.86 | FLT3 (0.43) | KDM4EALDH1A1HPGDLMNAFLT3 | |
| SCHEMBL6240318 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL30403281 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL11742020 | 0.83 | PLA2G4A (0.44) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL2492396 | 0.83 | IDO1 (0.51) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL11743428 | 0.83 | RHEB (0.51) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL3107966 | 0.80 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL8913109 | 0.79 | SRD5A2 (0.63) | KDM4EALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL8911576 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1HPGDLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060626-A | Indole-carboxylic carbon compounds and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1977-11-29 | — | — | US | claimed |
| US-4060626-A | Indole-carboxylic carbon compounds and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1977-11-29 | — | — | US | disclosed |