Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 17/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21823749 | 1.00 | FPR2 (0.51) | FPR2PTGER1PDE4BPDE4D | |
| SCHEMBL21823732 | 0.85 | FPR2 (0.51) | FPR2PDE4B | |
| SCHEMBL31095961 | 0.85 | FPR2 (0.51) | FPR2PDE4B | |
| SCHEMBL21918821 | 0.82 | FPR2 (0.47) | FPR2 | |
| SCHEMBL21823639 | 0.80 | FPR2 (0.50) | FPR2PDE4BPDE4D | |
| SCHEMBL31096180 | 0.80 | FPR2 (0.50) | FPR2PDE4BPDE4D | |
| SCHEMBL21823713 | 0.74 | FPR2 (0.47) | FPR2PDE4B | |
| SCHEMBL1965584 | 0.73 | PDE4A (0.65) | FPR2PDE4BPDE4D | |
| SCHEMBL31096168 | 0.73 | FPR2 (0.57) | FPR2 | |
| SCHEMBL21823420 | 0.73 | FPR2 (0.57) | FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166177-B | Boron-containing PDE4 inhibitors | 辉瑞公司 | 2024-09-03 | — | — | CN | disclosed |
| US-20230148402-A1 | Boron Containing PDE4 Inhibitors | PFIZER INC. (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148402-A1 | Boron Containing PDE4 Inhibitors | PDE4B, PDE4A, PDE3B | FPR2 3899/4885PTGER1 1848/4885PDE4B 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.