Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 2/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24174599 | 1.00 | MAPT (0.39) | MAPTPTGS2PTGS1LMNATSHR | |
| SCHEMBL24175435 | 0.90 | PTGS2 (0.39) | MAPTPTGS2PTGS1LMNATSHR | |
| SCHEMBL24170315 | 0.90 | CA1 (0.36) | MAPTTSHRMEN1KMT2APTGER4 | |
| SCHEMBL24175247 | 0.90 | HDAC1 (0.36) | MAPTPTGS2TSHRHSD17B10MEN1 | |
| SCHEMBL30404861 | 0.89 | PTGS2 (0.39) | MAPTPTGS2PTGS1LMNAHSD17B10 | |
| SCHEMBL24174600 | 0.89 | PTGS2 (0.39) | MAPTPTGS2PTGS1LMNAHSD17B10 | |
| SCHEMBL24174808 | 0.87 | KIT (0.31) | KITPTGER4 | |
| SCHEMBL25987124 | 0.86 | CA1 (0.34) | PTGS2PTGS1MEN1KMT2APTGER4 | |
| SCHEMBL24175262 | 0.85 | NPC1 (0.33) | CA12CA9NPC1RAB9A | |
| SCHEMBL24175628 | 0.85 | CA1 (0.37) | PTGS2PTGS1MEN1KMT2APTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4175961-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | Bayer Aktiengesellschaft (DE) | 2023-05-10 | — | — | EP | disclosed |