Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.30 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.30 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24110229 | 1.00 | MAPT (0.42) | MAPTHCRTR2ACSS2HTR2CHTR2A | |
| SCHEMBL25818045 | 0.82 | CYP1A2 (0.34) | HTR2CHTR2AGRM2PIK3CB | |
| SCHEMBL29904420 | 0.78 | HTR2C (0.57) | MAPTHCRTR2HTR2CHTR2A | |
| SCHEMBL24109810 | 0.78 | HTR2C (0.57) | MAPTHCRTR2HTR2CHTR2A | |
| SCHEMBL29904400 | 0.78 | HTR2C (0.54) | MAPTHTR2CHTR2AGRM2KDM4E | |
| SCHEMBL24110335 | 0.78 | HTR2C (0.40) | HTR2CHTR2ANR3C1 | |
| SCHEMBL24109924 | 0.78 | HTR2C (0.54) | MAPTHTR2CHTR2AGRM2KDM4E | |
| SCHEMBL24109932 | 0.77 | USP19 (0.32) | NR3C1 | |
| SCHEMBL25296144 | 0.76 | HTR2C (0.43) | MAPTHCRTR2ACSS2HTR2CHTR2A | |
| SCHEMBL24109986 | 0.76 | HTR2C (0.43) | MAPTHCRTR2ACSS2HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165049-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | Delix Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |