Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25166871 | 0.98 | ACHE (0.71) | ACHEEPHX1EPHX2 | |
| SCHEMBL6169501 | 0.95 | ACHE (0.70) | ACHEEPHX1EPHX2 | |
| SCHEMBL31122612 | 0.93 | ACHE (0.74) | ACHEEPHX1EPHX2 | |
| SCHEMBL7569673 | 0.91 | ACHE (0.81) | ACHEEPHX1EPHX2 | |
| SCHEMBL2592697 | 0.89 | ACHE (0.67) | ACHEEPHX1 | |
| SCHEMBL473096 | 0.89 | ACHE (0.85) | ACHEEPHX1EPHX2 | |
| SCHEMBL7785857 | 0.89 | ACHE (0.85) | ACHEEPHX1EPHX2 | |
| SCHEMBL473236 | 0.89 | ACHE (0.85) | ACHEEPHX1EPHX2 | |
| SCHEMBL10447924 | 0.89 | ACHE (0.85) | ACHEEPHX1EPHX2 | |
| SCHEMBL13387437 | 0.89 | ACHE (0.85) | ACHEEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168002-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2023-04-26 | — | — | EP | disclosed |