Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16466985 | 0.87 | ALDH1A1 (0.48) | ALDH1A1MAPTBTKKMT2AMEN1 | |
| SCHEMBL23084726 | 0.81 | BTK (0.53) | ALDH1A1MAPTBTKKMT2AMEN1 | |
| SCHEMBL21448744 | 0.81 | BTK (0.53) | ALDH1A1MAPTBTKKMT2AMEN1 | |
| SCHEMBL20347634 | 0.79 | TACR1 (0.50) | ALDH1A1MAPTBTKKMT2AMEN1 | |
| SCHEMBL13099512 | 0.78 | BTK (0.53) | ALDH1A1MAPTBTKKMT2AMEN1 | |
| SCHEMBL30672379 | 0.78 | BTK (0.53) | ALDH1A1MAPTBTKKMT2AMEN1 | |
| SCHEMBL15970021 | 0.76 | MEN1 (0.46) | ALDH1A1MAPTBTKKMT2AMEN1 | |
| SCHEMBL15970019 | 0.76 | MEN1 (0.46) | ALDH1A1MAPTBTKKMT2AMEN1 | |
| SCHEMBL23084817 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTBTKKMT2AMEN1 | |
| SCHEMBL27891265 | 0.76 | TACR1 (0.49) | ALDH1A1MAPTBTKKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444300-A2 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |