Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25269982 | 0.89 | MEN1 (0.42) | MEN1KMT2AHTTAURKA | |
| SCHEMBL25437860 | 0.86 | MEN1 (0.52) | MEN1KMT2A | |
| SCHEMBL25730044 | 0.86 | MEN1 (0.47) | MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL30405156 | 0.86 | MEN1 (0.52) | MEN1KMT2A | |
| SCHEMBL25224492 | 0.85 | MEN1 (0.43) | MEN1KMT2AHTT | |
| SCHEMBL25230921 | 0.84 | MEN1 (0.44) | MEN1KMT2AHTTACHEBACE1 | |
| SCHEMBL19032398 | 0.82 | MEN1 (0.51) | MEN1KMT2A | |
| SCHEMBL25730917 | 0.81 | MEN1 (0.60) | MEN1KMT2A | |
| SCHEMBL25633236 | 0.80 | HTT (0.52) | MEN1KMT2AHTTACHEBACE1 | |
| SCHEMBL25731207 | 0.80 | MEN1 (0.64) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444300-A2 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |