Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | BLM | P54132 | 3/20 | 0.73 |
| ▸ | HTR2A | P28223 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.73 |
| ▸ | HTR1A | P08908 | 2/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.73 |
| ▸ | HTR2C | P28335 | 2/20 | 0.73 |
| ▸ | HTR2B | P41595 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.73 |
| ▸ | HTR7 | P34969 | 1/20 | 0.73 |
| ▸ | MTOR | P42345 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29527694 | 1.00 | KMT2A (0.73) | KMT2ABLMHTR2AKDM4ELMNA | |
| SCHEMBL41267 | 1.00 | KMT2A (0.73) | KMT2ABLMHTR2AKDM4ELMNA | |
| SCHEMBL7614399 | 1.00 | KMT2A (0.73) | KMT2ABLMHTR2AKDM4ELMNA | |
| SCHEMBL41266 | 1.00 | KMT2A (0.73) | KMT2ABLMHTR2AKDM4ELMNA | |
| SCHEMBL18029004 | 1.00 | KMT2A (0.73) | KMT2ABLMHTR2AKDM4ELMNA | |
| Water SCHEMBL8346726 | 0.99 | KMT2A (0.71) | KMT2ABLMHTR2AKDM4ELMNA | |
| Tryptophan SCHEMBL18301515 | 0.94 | KDM4E (0.78) | KMT2ABLMHTR2AKDM4ELMNA | |
| Dl-Tryptophan SCHEMBL18301512 | 0.94 | KDM4E (0.78) | KMT2ABLMHTR2AKDM4ELMNA | |
| Dl-Tryptophan SCHEMBL28762527 | 0.94 | KDM4E (0.78) | KMT2ABLMHTR2AKDM4ELMNA | |
| Tryptophan SCHEMBL28762526 | 0.94 | KDM4E (0.78) | KMT2ABLMHTR2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240200049-A1 | COMPOSITIONS AND METHODS OF USE THEREOF FOR MAKING POLYPEPTIDES WITH MANY INSTANCES OF NONSTANDARD AMINO ACIDS | YALE UNIVERSITY | 2024-06-20 | — | — | US | disclosed |
| US-11649446-B2 | Compositions and methods of use thereof for making polypeptides with many instances of nonstandard amino acids | YALE UNIVERSITY (US) | 2023-05-16 | — | — | US | disclosed |