SCHEMBL41267

SCHEMBL41267

Cc1ccc2[nH]cc(CC(N)C(=O)O)c2c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.73
BLM P54132 3/20 0.73
HTR2A P28223 3/20 0.73
KDM4E B2RXH2 2/20 0.73
LMNA P02545 2/20 0.73
MAPT P10636 2/20 0.73
TSHR P16473 2/20 0.73
PMP22 Q01453 2/20 0.73
NPSR1 Q6W5P4 2/20 0.73
HTR1A P08908 2/20 0.73
NFKB1 P19838 2/20 0.73
HTR2C P28335 2/20 0.73
HTR2B P41595 2/20 0.73
ALDH1A1 P00352 1/20 0.73
CYP3A4 P08684 1/20 0.73
ADORA3 P0DMS8 1/20 0.73
ALOX15 P16050 1/20 0.73
SLC6A4 P31645 1/20 0.73
HTR7 P34969 1/20 0.73
MTOR P42345 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29527694 1.00 KMT2A (0.73) KMT2ABLMHTR2AKDM4ELMNA
SCHEMBL30406433 1.00 KMT2A (0.73) KMT2ABLMHTR2AKDM4ELMNA
SCHEMBL7614399 1.00 KMT2A (0.73) KMT2ABLMHTR2AKDM4ELMNA
SCHEMBL41266 1.00 KMT2A (0.73) KMT2ABLMHTR2AKDM4ELMNA
SCHEMBL18029004 1.00 KMT2A (0.73) KMT2ABLMHTR2AKDM4ELMNA
Water SCHEMBL8346726 0.99 KMT2A (0.71) KMT2ABLMHTR2AKDM4ELMNA
Tryptophan SCHEMBL18301515 0.94 KDM4E (0.78) KMT2ABLMHTR2AKDM4ELMNA
Dl-Tryptophan SCHEMBL18301512 0.94 KDM4E (0.78) KMT2ABLMHTR2AKDM4ELMNA
Dl-Tryptophan SCHEMBL28762527 0.94 KDM4E (0.78) KMT2ABLMHTR2AKDM4ELMNA
Tryptophan SCHEMBL28762526 0.94 KDM4E (0.78) KMT2ABLMHTR2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3529 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118895127-A Tartaric acid functionalized fluorescent carbon quantum dot for Cr (VI) double-channel detection and oxidation removal, and preparation method and antibacterial application thereof 中国海洋大学 2024-11-05 CN claimed
CN-118184756-A Engineered Leptospira perfoliatum lectin mutant and application thereof 浙江大学医学院附属第一医院(浙江省第一医院) 2024-06-14 CN claimed
US-20240076317-A1 CELL-REACTIVE, LONG-ACTING, OR TARGETED COMPSTATIN ANALOGS AND USES THEREOF SIXTH STREET LENDING PARTNERS 2024-03-07 US claimed
CN-116836959-A Enzyme composition for synthesizing neomycin derivative and application thereof 山东大学 2023-10-03 CN claimed
US-11752131-B2 Methods and pharmaceutical compositions for the treatment of obesity INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2023-09-12 US claimed
US-11661441-B2 Cell-reactive, long-acting, or targeted compstatin analogs and uses thereof APELLIS PHARMACEUTICALS, INC. (US) 2023-05-30 US claimed
US-11629357-B2 DNA constructs for obtaining marker-free transgenic plants MONSANTO TECHNOLOGY, LLC (US) 2023-04-18 US claimed
EP-4105224-A1 LONG-ACTING COMPSTATIN ANALOGS AND USES THEREOF Apellis Pharmaceuticals, Inc. (US) 2022-12-21 EP claimed
US-20220256900-A1 COMPOSITIONS WITH SUGAR LIKE CHARACTERISTICS CHROMOCELL CORPORATION 2022-08-18 US claimed
EP-3982756-A1 COMPOSITIONS WITH SUGAR LIKE CHARACTERISTICS CORN Products Development Inc. (US) 2022-04-20 EP claimed
EP-0183006-A2 A recombinant DNA-molecule, coryneform bacteria carrying recombinant DNA and process for producing an aromatic amino acid by using the same AJINOMOTO CO., INC. (JP) 1986-06-04 EP claimed
US-4581847-A Tryptophan overproducer mutants of cereal crops MOLECULAR GENETICS RESEARCH AND DEVELOPMENT (US) 1986-04-15 US claimed
EP-0174791-A2 Tryptophan overproducer mutants of cereal crops MOLECULAR GENETICS RESEARCH & DEVELOPMENT LIMITED (US) 1986-03-19 EP claimed
US-4560652-A BACILLUS MUTANT AZASERINE, METHYL-TRYPTOPHAN AND FLUORO-TRYPTOPHAN RESISTANT; FEEDS AJINOMOTO CO., INC. (JP) 1985-12-24 US claimed
EP-0136359-A1 PROCESS FOR PREPARING L-HISTIDINE KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1985-04-10 EP claimed
EP-0081107-A2 Process for producing L-tryptophan by fermentation AJINOMOTO CO., INC. (JP) 1983-06-15 EP claimed
US-4371614-A E.Coli bacteria carrying recombinant plasmids and their use in the fermentative production of L-tryptophan AJINOMOTO CO., INC. (JP) 1983-02-01 US claimed
US-4283337-A Process for the purification of tryptophane and derivatives of tryptophane DEUTSCHE GOLD UND- SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-08-11 US claimed
US-3963572-A Fermentative process for the production of L-tryptophan and its derivatives AB BOFORS (SW) 1976-06-15 US claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed